Sentence examples for mediates association with from inspiring English sources

In Drosophila S2 cells, tethering of LacI-CENP-ACID to LacO arrays inserted on a chromosome arm recruits kinetochore components and mediates association with microtubule fibres [ 46 ].

Alternative splice variants of TAF4 lack parts of the TAF homology domain, which mediates association with a variety of transcriptional factors.

SpnP possesses a structural feature that has only been previously observed in the related glycosyltransferase EryCIII, in which it mediates association with the auxiliary protein EryCII.

The cytoplasmic tail of Notch ligands drives endocytosis, mediates association with proteins implicated in the organization of cell-cell junctions and, through regulated intra-membrane proteolysis, is released from the membrane as a signaling fragment.

The first amino acid substitution (T20I) is close to the Leu-Xaa-Cys-Xaa-Glu domain that mediates association with the retinoblastoma protein (pRb) and its related proteins, p107 and p130.

Recent data indicate that efficient nuclear import can involve the microtubule (MT)/dynein network, such that nuclear delivery of exogenous cargo could be enhanced by attachment to peptide modules mediating association with dynein components, but this has not been investigated.

The resulting fusion protein has no DNA binding motifs but possesses protein-protein interaction domains that are believed to mediate association with chromatin remodeling complexes.

The hGBPs are isoprenylated at their C-terminus via the CAAX domain, and the addition of this hydrophobic tag is thought to mediate association with membranous structures [21], [26], [36].

These data suggest that TDP-43 can bind to TIA-1 at higher concentrations of TDP-43, such as with over-expression, but that binding to TIA-1 is not the predominant mechanism mediating association with SGs under basal levels of TDP-43 expression.

Thus fly APC2's Arm rpts can mediate association with Axin's middle region.

The p.L95F mutation is located in the conserved BTB domain of KLHL9, which mediates interaction with Cul3, while the Kelch repeats mediate association with substrates.