Sentence examples for mediates interaction with from inspiring English sources

Further, it has been shown that NEMO contains a K63-specific ubiquitin-binding domain, required for IL-1-mediated IKK activation, which mediates interaction with ubiquitinated IRAK-1, but not ubiquitinated TRAF6 [41], [41].

Next, we mapped the region within Ezh2 that mediates interaction with the HECT domain of Smurf2.

The IbeA invasin of adherent-invasive Escherichia coli mediates interaction with intestinal epithelia and macrophages.

In particular, we show that this motif mediates interaction with the SH3 domain of NPHP1 to assemble into a novel, previously unrecognized complex.

The PH domain works as a binding motif for phosphatidylinositol 4,5 biphosphate, and the PRD domain mediates interaction with various proteins containing SH3 domains [14].

The E2 protein contains a single motif that mediates interaction with both E1 and E3, signifying the "shuttle" status of E2 in the transfer of ubiquitin/UBLps between activation and subsequent ligation to their final target.

Dimerization involves the TRF homology (TRFH) domain, which also mediates interactions with other telomeric proteins.

The CP190 interaction module encompasses a sequence ~200 amino acids long that spans the C-terminal and mediates interactions with the N-terminal BTB domain of the CP190 protein.

It has been shown that exposed positioning of the proline rich loops mediates interactions with other proteins [28].

In animals, many of the partners of HP1 contain the PxVxL consensus pentapeptide, which mediates interactions with the chromo shadow domain (CSD) of HP1 proteins [44] [48].

The RING1 domain mediates interactions with the E2 enzyme.