Sentence examples for mediates dimerization with from inspiring English sources

Sequence similarity in these clades was mostly restricted to the C-terminal proline-rich motif, which mediates dimerization with the ubiquitin-ligase Fbxo7 (Kirk et al. 2008).

Some of these genes are also dysregulated by HOXA9 and/or HOXA9ΔN (Fig. 11A), suggesting that their dysregulation is mediated by non-DNA-binding parts of the homeodomain such as those that mediate dimerization with other proteins [53].

The RD contains two distinct functional surfaces – one involved in DNA binding (composed of 10 functional residues) and one mediating dimerization with CBFβ.

The N-terminal extension mediates dimerization and tetramerization, with extensive interactions and distinct interfaces.

It selectively recruits substrates via its N-terminal MATH domain, whereas its BTB domain mediates dimerization and interaction with CUL3.

Like their vertebrate counterparts, these fly proteins contain an approximately 300-amino acid long, multifunctional and conserved Rel homology domain, which mediates dimerization, DNA binding, and interactions with IκB inhibitor proteins [ 7- 9].

Proteins of this family harbour a Rel homology domain, which mediates dimerization as well as the interaction with inhibitory components of the pathway.

Nevertheless, LP17 overlaps the CDR-3 and the 'F' β strand of the extracellular domain of TREM-1, with the 'F' β strand containing a tyrosine residue that mediates dimerization.

The N-terminal domain of ionotropic glutamate receptors mediates dimerization [11] and affects ligand affinity [12].

The N-terminal tail mediates dimerization, and binds accessory chains and cargo.

The conserved GGLVG transmembrane domain of syndecan-1 mediates dimerization [ 58, 59].