Sentence examples for mediates a specific from inspiring English sources

Our data indicate that Sec15 mediates a specific vesicle trafficking event to ensure proper neuronal fate specification in Drosophila.

CEM/VM-1 harbors a mutated topoisomerase II gene which mediates a specific resistance to topoisomerase II inhibitors, but not general multidrug resistance [19], [20].

However, it remains unclear if ICP0 mediates a specific function in the cytoplasm of HSV-1 infected cells, or if ICP0 translocates to the cytoplasm for the sole purpose of its incorporation into HSV-1 virions [26], [27], [28], [29].

Each subset of genes, whose regulated expression mediates a specific biological effect of PCFS4, shares a common cis-element.

The Saccharomyces cerevisiae p38 homolog Hog1 is primarily activated by osmotic stress and mediates a specific program of gene expression to combat and adapt to high osmolarity [ 5].

Subsequently, the phosphoryl group is transferred to an aspartate residue of the cognate response regulator, which then becomes active and mediates a specific response, usually by activating and/or repressing a set of target genes.

The uniqueness of the interaction with PYL8 (and with no other PYL) provides an example of receptor specificity - an ABA receptor mediating a specific sub-network of responses.

In the case of ETS1 and ETS2, for example, the structure of the pointed domain can mediate a specific ERK2 interaction [ 52], consistent with the ERK2 specificity we observed in Figure  1.

These clones displayed a CD4+CD8dim+ (TC5) and CD4+ CD8– (TC7) phenotype and mediated a specific major histocompatibility complex class I-restricted cytotoxic activity toward Cou-LB autologous tumor cell line.

Since most networks mediating a specific biological function consist of multiple TFs and their- sometimes overlapping- TGs, the capacity to detect TGs genome-wide and in silico with high accuracy would bring major advantages.

In addition, although the complete role of Tetherin in mammals remains unclear, limited data show that Tetherin can (at least) mediate a specific feedback mechanism to turn off interferon production by plasmacytoid dendritic cells [8], [47].