Sentence examples for mediates a major from inspiring English sources

Although Chk1 mediates a major G2 checkpoint that delays mitosis, additional checkpoint pathways exist that delay entry into or progression through S phase.

Accordingly, we suggest that loss of synaptic Homer1b and mGluR1 mediates a major part of the impact of Aβ on synaptic physiology [cf. 53] [55].

PKA mediates a major signalling pathway that is crucial for linking stress responses and cell proliferation.

The gene encoding p53 mediates a major tumor suppression pathway that is frequently altered in human cancers [ 18].

They showed that the effect on disease regulation was larger than the effect from any of the smaller congenic strains, however one small (1.25 Mb) congenic strain (R23) mediates a major part of the regulatory effect from this region.

Letters soon followed, from strangers expressing a kinship to Mediate, a major contender of common mien.

Notably, sAPP α has neuroprotective and memory enhancing properties [ 10, 11], hypothesizing that sAPP α might mediate a major physiological function of APP [ 12].

Subsequently, Kellett's (my) laboratory proposed that the "diffusive" component is mediated by the glucose- and SGLT1-dependent transient insertion of the low affinity basolateral transporter GLUT2 into the apical membrane at high glucose concentrations, so that GLUT2 then mediated a major pathway of transcellular glucose absorption -.

47 For example, the multigene var family of Plasmodium falciparum encodes the surface protein PfEMP1, which induces immunodominant antibody responses and mediates cytoadherence, a major factor in pathogen survival and virulence.

Politics and World War II, mediated by a major poet.

These clones displayed a CD4+CD8dim+ (TC5) and CD4+ CD8– (TC7) phenotype and mediated a specific major histocompatibility complex class I-restricted cytotoxic activity toward Cou-LB autologous tumor cell line.