Sentence examples for mediates a substantial from inspiring English sources

Breen and Jonsson (2005) found evidence for the fact that further education mediates a substantial part of the association between social origin and career outcomes (Breen and Jonsson 2005).

Together these results indicated that Stat3 mediates a substantial portion of the effect of IL-6 in preventing cardiomyocyte apoptosis.

Furthermore, unlike PBA, SAHA mediates a substantial increase in synthesis of ATZ through a transcriptional activation mechanism.

IL-1 mediates a substantial portion, but not all, of TNF-α-induced osteoclast recruitment in inflammatory osteoclastogenesis [ 80] (Fig. 2).

As noted above, if IR mediates a substantial portion of IGF-stimulated tumour cell biology, especially via IGF-II activation, then cancer cell inhibition of IR would be necessary.

These secreted antiviral entry inhibitory (SAVE) peptides mediated a substantial protective bystander effect on neighboring nonmodified cells, thus suppressing virus replication even if only a small fraction of cells was genetically modified.

Much evidence suggests that the kinases Akt and Erk mediate a substantial part of the HER signaling [ 1].

We also show that Msn2 and Msn4 are important for mediating a substantial part of the transcriptional response induced by alkalinization of the medium.

Other biomarkers such as adiponectin, which could potentially mediate a substantial part of the association, should be included in such studies as well.

Nonetheless, previous data from this and other laboratories have described a cAMP-independent pathway mediating a substantial part of the vasorelaxant responses of PGI2 analogues in blood vessels [26 28].

This viewpoint is intellectually pernicious because it blinds researchers to the processes that actually drive molecular evolutionary change and to well-established consequences of gene-level selection, such as genomic conflicts, that mediate a substantial proportion of human disease risk.