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Docking results suggest that, the triazole nitrogen showed Zn+2 mediated interactions with the histidine residue of HDACs.
The terminal methoxy oxygen at R1 mediated interactions with the wild type protein's amino group of Asp29 and Asp30 with the distance of 2.29Å and 1.7Å, respectively.
Most of this virus is trapped on the surfaces of FDCs as immune complexes along the network of dendrites, which play a critical role in antigen mediated interactions with both T cells and B cells.
The permalloy nanoelements were also simulated to determine the remanent spin configuration and were designed to be bound by antibody mediated interactions with biological ligands at the receptor sites in order to act as a biosensor.
Similar(55)
Instead, it clearly depends on a PDZ-ligand mediated interaction with one or more PDZ domain-containing proteins [49].
This step can be catalysed by the RING1-IBR mediated interaction with an E2∼Ub thioester.
Delineation of ERα mediated interaction with distinct region of the promoter for estrogen-responsive genes in vivo in target tissues has been limited.
The presence of a Glu-Lys-Gly triplet in the middle of the sequence appears to mediate this staggered molecular packing through its indirect water-mediated interactions with backbone CO groups and side-chains.
These data indicate that RhoE mediates an indirect inhibitory effect on ROCK-I through effector site-mediated interactions with regulators of RhoA signalling.
This is exemplified by the 4bc derivative, which interacts directly with Leu214 and Arg119, and also has two water-mediated interactions with Glu116, strongly tying the ligand-binding site.
Many applications of nanobiomaterials rely on or are enhanced by specific, protein-mediated interactions with biological systems.
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