Sentence examples for regulated interactions with from inspiring English sources

It has long been hypothesized that the C-termini of cryptochromes are important for distinguishing their species-specific functions (Green, 2004) and for enabling regulated interactions with protein and possible nucleic acid partners (Czarna et al., 2011; Zoltowski et al., 2011; Engelen et al., 2013).

It is through these regulated interactions with cell populations and signalling pathways within the bone marrow microenvironment that myeloma cells are believed to 'hijack' the normal hematopoietic niche to aid the extensive growth and proliferation of tumour cells (see Figure 1).

Expansion of the tourism sector as a dollar industry was central to efforts to raise revenue, as Cuba began limited and regulated interaction with the global capitalist economy.

Since this residue is far from the DNA-binding domain, it is a better candidate for regulating interactions with coactivators.

Signals mediated by receptor tyrosine kinases (RTKs), such as stresses, growth factors, antigens, among many others, lead to the phosphorylation of hundreds of tyrosine residues leading to conformational changes that allosterically regulates interactions with specific binding partners[2], [3].

(B ) The acidic tail of RanQLGTP negatively regulates interactions with Slx9.

As discussed previously, SFKs also phosphorylate tyrosines on β-integrin tails, thus regulating interactions with cytoplasmic signaling molecules.

We recently reported that raft affiliation of CD44 negatively regulates interactions with its migratory binding partner ezrin.

Specific phosphorylated residues may thus promote or inhibit interactions between proteins or protein domains, or regulate interactions with small molecule substrates or ligands (40, 41 ).

First, protein kinases adopt similar inactive DFG-out conformation and use similar amino acid types to regulate interactions with type-II inhibitors.

Viewed in this context, the docking of the Sac3 PCI domain onto the Med31/Med7N submodule could locally alter Mediator conformation and thereby regulate interactions with Pol II.