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Clémenceau, B. et al. Antibody-dependent cellular cytotoxicity (ADCC) is mediated by genetically modified antigen-specific human T lymphocytes.
We compare biophysically and energetically the cellular responses to direct electrical current injection versus optical stimulation mediated by genetically expressed light-sensitive ion channels, e.g., Channelrhodopsin-2 (ChR2).
This minireview explores the environmental bioremediation mediated by genetically engineered (GE) bacteria and it also highlights the limitations and challenges associated with the release of engineered bacteria in field conditions.
How, then, might sexual antagonism be mediated by genetically based effects of hormonal variation?
Accumulating evidence indicates that susceptibility to cancer is mediated by genetically determined differences in the effectiveness of carcinogen detoxification.
Furthermore, we provide evidence that mitochondrial hyperfusion and UPRmt are coordinated but mediated by genetically distinct pathways.
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The catalytic activity of Topo II in mammalian cells is mediated by two genetically distinct isoenzyme forms, designated Topo II α and Topo II β, (Mw: 170 000 and 180 000, respectively) (Wang, 1996).
The aetiology of POAG is poorly understood, with both genetic and environmental factors contributing to the pathophysiology [ 3, 4] Irrespectively of the causative factors leading to visual loss, most of which are still not understood, the final common pathway in POAG is retinal ganglion cell death, mediated by apoptosis, a genetically regulated process [ 5].
In addition, susceptibility to norovirus is genetically mediated by the presence of a functional FUT2 gene [ 2], as this enzyme is needed for the synthesis of ABO HBGAs.
Since the effect of maternal smoking during pregnancy may be due to correlated genetic risk factors rather than being a pure environmental effect, we examined the effect of prenatal exposure to smoking on attentional control, taking into account the effects of both maternal and paternal smoking, and examined whether these effects were genetically mediated by parental genotypes.
In sum, the main aim of this study is to examine the effect of prenatal exposure to maternal and paternal smoking on attentional control in children with ADHD and control children, and examine whether these effects are genetically mediated by parental genotypes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com