These two databases are mediated by a third "linkage" database that contains a list pairing the two numerical codes for each patient.
In this system, the oxidation of thiosulfate (S2O32−) to sulfate entails the oxidative linkage, mediated by SoxXA, of thiosulfate to the conserved C-terminal cysteine of SoxY, followed by hydrolysis of the terminal sulfone (SO3−) group by SoxB (Figure S7B).
Since topo II is required for the resolution of sister chromatid catenations [ 95], it is conceivable that sister chromatid intertwinings might restrict the formation of long-distance linkages by condensin II in a similar manner as sister chromatid linkages mediated by cohesin might do.
Additionally, we investigated whether G-quadruplex formation in U3 RNA promotes viral recombination and the implications for a general viral recombination mechanism mediated by periodically spaced genome linkages including those that occur in U3 together with previously reported linkages in the gag and cPPT regions.
This result strengthens the view that DSBs are required to establish SCC, but the requirement is partially masked by sister linkages mediated by SC proteins.
The dynein-nuclear envelope connection in mammalian cells is mediated by three nonredundant molecular linkages and is required both for the attachment of the centrosomes to the nucleus and for their proper separation during prophase (Splinter et al. 2010; Bolhy et al. 2011; Jodoin et al. 2012).
Strong correlations among leaf biomass, above-ground biomass (also its percentage), and total biomass 16 in year 1 may be due to a pleiotropic QTL detected on linkage group 4. It turns out that these correlations in year 2 are mediated by a different QTL on linkage group 13.
Thus, the linkage was mediated by carbinolamine/imine chemistry (Scheme 4).
The linkage of caspase-8 polyubiquitin chains mediated by HECTD3 was analyzed by using linkage-specific antibodies that specifically recognize K48- or K63-linked polyubiquitin chains under denaturing conditions.
Since accumulation of fluorescently labeled streptavidin was absent if the DNA strands were not complementary (cp. Figure 4.D.2), both DNA-independent vesicle aggregation mediated by streptavidin [29] and linkage-independent crystallization of streptavidin [59] can be ignored as factor of adhesion plaque formation.
These linkages are mediated by SCC-1 cohesin, previously believed to function only during mitosis.
