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Activated RA synovial fibroblasts (SFs) mediate the invasion and destruction of cartilage and bone.
The site specificity that avian Eimeria sporozoites and, to a more limited degree, other apicomplexan parasites exhibit for invasion in vivo suggests that specific interactions between the sporozoites and the target host cells may mediate the invasion process.
This study demonstrates, for the first time, that fibrillar collagens are extensively deposited in GBMs and that the collagen internalization receptor Endo180 is both highly expressed in these tumors and that it serves to mediate the invasion of tumor cells through collagen-containing matrices.
It is known that proteoglycans secreted from the tumor cells was not only responsible for the formation of basement membranes, but also mediate the invasion of tumor cells.
Fibronectin (Fn -binding proteins have been reported to mediate the invasion oFn -bindings without the need for other bacterial factors [ 46].
Similar(55)
These data suggest that CXCR3 activation by its cognate ligands appears as a common feature of the CRC cells from distinct origins and that it could mediate the invasion-related properties of colon cancer cells.
Because of their ubiquity and presumed low level of host specificity, arbuscular mycorrhizal fungi (AMF) have been generally believed to play a minor role in mediating the invasion of exotic plants [1].
This nuclear localisation is critical in mediating the invasion of PSCs and, consequently, cancer cells.
In teleosts, however, the molecular mechanisms mediating the invasion of immune cells in atretic follicles are largely unknown.
RAD51 is responsible for mediating the invasion of the sister chromatid to find homologous sequence partners, thus representing a key component of the HR pathway.
If zTGF-β would have contributed to mediating the invasion and metastatic response we would have also expected elevated pSmad2 staining in the host tissue surrounding the tumour.
Related(20)
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