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In addition, network reconstruction has an advantage over traditional gene-level clustering analysis in that the network provides insight into which subnetworks interact with each other and which nodes/genes might mediate such interactions.
These steps involve interactions between proteins, and the specific amino acids that mediate such interactions have been elucidated.
Despite the fact that interaction with host-cell membranes is a central theme in the Plasmodium life cycle, little is known about parasite proteins that mediate such interactions.
Most of the ribosomal K-turns help mediate such interactions.
Additional studies will need to delineate domains in NO66 that mediate such interactions.
Furthermore, CK2-phosphorylated GST-SDTD2 retrieved NBS1 and RAD50 from both MRC5- and NBS1-complemented Nijmegen breakage syndrome (NBS) cell extracts, but did not mediate such interactions when the FHA domain mutant of NBS1 was expressed in NBS cells (Fig 3C; see supplementary Fig S2 online for expression levels).
Similar(53)
A number of motifs have now been shown to mediate such interaction of effectors with activated Ras family proteins: here, we will discuss in more detail recent advances on the first such domain originally identified in c-Raf and involved in Ras-GTP interaction, the self-titled Ras-Binding Domain (RBD).
Still, parasite ligands mediating such interactions have not been unequivocally identified.
This finding is consistent with the hypothesis that cellulose synthesis is coupled with cortical microtubules (Goddard et al 1994; Roberts et al 2004; Oda et al 2005), and suggests that PttMAP20 may have a role in mediating such interactions in poplar secondary cell walls.
In this study, we examined (1) the role of uncertainty avoidance in influencing the effects of concrete vs. abstract CSR messages on attitude toward the company and purchase intention and (2) the role of perceived message clarity and perceived CSR in mediating such interaction effects.
Absence of the co-immunoprecipitating band of CypD and TRAP1 in mutant cells is indicative of the specific role played by JC15 in recruiting CypD to MPTP complex and critical role of a functional J-domain in mediating such interaction.
Related(20)
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