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Receptors are highly regulated cell surface proteins that mediate specific interactions between cells and their extracellular milieu, and they are generally localized to the plasma membrane [36].
Other modular signaling domains were soon found to mediate specific interactions with other peptides or lipids.
Mtb capsular carbohydrates are absent in some other taxa and mediate specific interactions with the host [ 9].
In these examples, structured domains mediate specific interactions to form assemblies that serve as scaffolds for further assembly of components of membrane-less organelles.
However, there is considerable diversity in the means by which these inserts mediate specific interactions, both between and within different superfamilies of this clade.
As discussed above, the N-terminal and C-terminal regions, along with the CATD, mediate specific interactions that distinguish CENP-A from H3 nucleosomes.
Similar(51)
The functional hallmark of disorder is its ability to mediate specific interaction with multiple binding partners1, 15.
The ankyrin repeat region of IκBα mediates specific interactions with NF-κB dimers, but ankyrin repeats 1, 5 and 6 display a highly dynamic character when not in complex with NF-κB.
We showed that this region, together with the preceding hydrophobic region, mediates specific interactions of SAP30/SAP30L with the monophosphoinositides (PIPs) PdtIns3P, PtdIns4P and PtdIns5P.
In the case of SVR3/AtcpTypA, the C-terminal domain may play a crucial role in mediating specific interactions between TypA and the ribosome at chilling temperature by mediating specific translation events.
Given that the proof of biological specificity is a major challenge for all in vitro systems, we first focused on proving that this biomimetic surface mediated specific interactions between neutrophils and GPIbα.
More suggestions(13)
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mediate specific functions
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mediate specific signals
mediate specific patterns
mediate fundamental interactions
mediate ecological interactions
mediate electromagnetic interactions
mediate specific activities
mediate specific aspects
facilitating specific interactions
regulate specific interactions
facilitate specific interactions
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