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We report a new method of measuring visual function in patients with INS by demonstrating the effects of eccentric gaze and forced time restriction on optotype recognition.
To this aim, we first investigated the visual functions of EAE mice using multifocal electroretinograms (mfERGs), an established noninvasive method for effectively measuring visual function [16], [17].
The ability of atropine to enhance retinal function has implications for the interpretation of data arising from a range of visual neuroscience studies that employ this drug prior to measuring visual function [12], [63], [65].
We next investigated visual functions of cuprizone-treated mice using multifocal mfERGs, an established non-invasive method for effectively measuring visual function.
It is hoped that future trials will go beyond measuring visual function and will include recently developed individualised measures of QoL [ 42, 44].
We next investigated the visual functions of EAE mice using multifocal electroretinograms (mfERG), an established non-invasive method for effectively measuring visual function (Harada et al, 2007).
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The TyPE questionnaire, a validated 67-item questionnaire measuring visual functioning relative to multi-focality [ 5], showed that ReSTOR® was able to significantly improve near vision without glasses after cataract surgery, compared to AcrySof® mono-focal IOLs, allowing the majority of ReSTOR®-implanted patients to be free of glasses [ 15, 16].
Our aim was to gather detailed information about the clinically measured visual function, the perceived level of vision, and the visual history of each participant.
The authors' objective was to measure visual function and quality-of-life outcomes associated with bilateral implantation of a multifocal IOL, which corrects distance and near vision, and to compare the outcomes with those of the standard therapy.
Discrepancies between perceived and clinically measured deficits in vision may arise because clinical measures do not reflect the visual demands on-the-field or because some reduction in clinically measured visual function can exist without impacting on perceived vision on the field (or both).
In addition, we measured visual function of EAE mice in vivo, and showed mild visual disturbance in ASK1−/− mice.
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