Sentence examples for may underlie altered from inspiring English sources

IL-6 was chosen for further investigation to determine the signaling pathway that may underlie altered expression based on its well characterized role in hematopoiesis.

(iii) Third, genes associated with lipid metabolism may be down-regulated in epidermal cells from PP skin [ 4], and this effect may underlie altered phospholipid abundance in PP skin [ 30- 32].

Changes in fatty acid synthase, Spot 14, Akt, and DecR1 (2,4-dienoylcoenzyme A reductase) may underlie altered lipid metabolism in tumor cells and contribute to the ability of tumor cells to proliferate or metastasize.

Our data demonstrate greater numbers of VIP-and VP-positive cells and greater FOS expression in response to light and in CBA/J mice, which may underlie altered central processing of photic signals.

Regulatory regions, as demarcated by DNAse hypersensitivity sites, have been shown to be enriched for epigenetically variable loci (13), providing support for the conjecture that epigenetic variability may underlie altered expression patterns and thus modulate disease.

An altered RNA binding preference of mutant RBPs could also underlie altered RNA granule formation [ 84].

Hence, it is conceivable that altered stress-strain relationships, owing to intraventricular and interventricular dyssynchrony, may be important factors underlying altered intracellular gap junction distribution in the left bundle branch block model, as well as in our model of epicardial right ventricular pacing.

These results implicate changes in neuropeptide expression in the SCN which may underlie the altered circadian responses to light in these animals.

These data suggest that the mechanisms underlying altered DAT function may have an impact when using DAT radioligands.

The investigation of total upper and lower limb lengths, as well as limb segment lengths, may help to elucidate the mechanisms underlying altered body proportions under stress conditions (Pomeroy et al., 2012).

Our results offer a 'side' view of CPVT, in which the occurrence of calcium transient initiation at multiple foci constitutes the arrhythmogenic substrate by underlying altered gating kinetics of RyR2 (which may explain the double upstroke).