Sentence examples for may represent downstream from inspiring English sources

dunce-like optomotor phenotypes in D0264, D0067, and D0177 suggest that these mutations might compromise brain circuits relevant to dunce function (i.e., they may represent downstream plasticity genes expressed in the same cells as dunce).

Kallikreins, being under steroid hormone regulation, may represent downstream targets by which hormones influence the initiation or progression of cancer.

The bacteria may target these host factors directly while some induced genes may represent downstream effects due to the presence of the bacteria.

In addition, profiling has been exploited to identify ncRNAs that may represent downstream targets of activated oncogenic pathways or that are targeting protein coding genes involved in cancer.

Hypoxia and PGs have been associated with these increases in VEGF expression (Fan et al., 2008; Maybin et al., 2011b) and may represent downstream mediators of progesterone withdrawal.

It is our hypothesis that the twenty genes upregulated in flies whose life span is extended by DR, dSir2 or DN-Dmp53 may represent elements downstream in the DR life span extending pathway.

In Parkinson disease (PD), sarcopenia may represent the common downstream pathway that from motor and nonmotor symptoms leads to the progressive loss of resilience, frailty, and disability.

Our results provide further evidence that Rap1 may represent an important downstream effector of JAM-A in the development and progression of breast cancer.

These cutoffs of 1.5 or 0.5 were chosen given that small changes in gene expression may represent important changes downstream of those differentially expressed genes.

Remarkably, the formation of ubiquitin/p62-positive inclusions remained intact after these manipulations, suggesting that Tau-mediated neurodegeneration may represent (i) a downstream pathological event of abnormal protein aggregation, or (ii) a parallel phenomenon triggered by an unknown mechanism.

That oxidative stress is a pathological hallmark of these and other neurodegenerative disorders suggests that DNA damage arising from ROS may represent a general downstream consequence of disease pathogenesis, not necessarily due to defects in FUS function.