Sentence examples for may modulate downstream from inspiring English sources

Enhanced expression of miR-155 in RA synovial fibroblasts revealed matrix metalloproteinase 3 (MMP-3) as a potential target of miR-155, suggesting that miR-155 may modulate downstream tissue damage (Stanczyk et al., 2008).

Thus, GAGs/PGs may modulate downstream signaling of key cellular mediators including insulin growth factor receptor (IGFR), epidermal growth factor receptor (EGFR), estrogen receptors (ERs), or Wnt members.

Thus, the present study suggests that OSM-9/OCR-2 TRPV channels may serve as sensor molecules for strongly alkaline pH, and that GOA-1 may act to modulate downstream signaling of TRPV channels in ASH.

Because Daple enhances non-canonical Wnt signaling that is initiated by FZDRs, we asked how Daple may modulate signals downstream of these receptors and wondered if they interact.

It is thus inviting to speculate that NGF plus Col 1 and UG26 CM may modulate similar downstream pathways to block apoptosis, as suggested by our finding of a differential expression of genes in the "Apoptosis" REACTOME pathway following UG26 CM exposure, and the similar relative decrease in Annexin V staining of ESLAM cells incubated with either of these additives.

It is possible to hypothesize that RASSF5 may interact with the transcriptional regulators in addition to Itch to modulate downstream signaling pathway to control cell proliferation.

They also modulate downstream signaling pathways such as those for ERK and NF-κB independent of receptor desensitization.

GRB14 binds the receptors for insulin (IR) and IGF1 (IGF1R) to modulate downstream signaling [ 19- 22].

Mechanisms are proposed by which receptors can modulate downstream responses together and independently.

Our results showed that EPO can modulate downstream mitochondrial biogenesis and haemoglobin induction in neuronal cells.

Another likely mechanism by which receptor His kinase activity could modulate downstream signalling is through a His-Asp phosphorelay involving downstream phosphotransfer proteins and response regulators.