Sentence examples for may represent alterations from inspiring English sources

These stage-specific miRNA profiles may represent alterations in exosomally secreted miRNAs during cancer progression.

Differences between profiles may represent alterations in specific signalling pathways, so mapping this information onto a timeline of when mutations occur in breast cancer will enable clinicians to tailor specific treatments to individuals.

The few exceptional sites subject to positive selection found in the triple stranded β-sheets that form the structural core of the β-defensins, may represent alterations in the oligomerisation of β-defensins.

By integrating data on CNAs and the previously identified 3-miRNA expression signature, we were able to show a possible interaction between these changes; these may represent alterations to genomic and post-transcriptional control mechanisms of specific genes and pathways important for disease progression.

Moreover, previous analyses found GATA5 hypermethylation in human malignancies such as gastric and colorectal cancers and demonstrated that epigenetic silencing of the gene occurred in various human cancer cell lines, providing evidence that GATA5 alterations may represent epigenetic alterations of wider relevance for carcinogenesis [ 4, 6].

These initial changes may represent important alterations of physiological pathways that culminate in altered protein turnover and/or recruitment of satellite cells to support muscle growth.

Some of which may represent background alterations with no specific involvement in the carcinogenesis process.

Therefore, the smallest regions of overlap between all samples, namely 3q24-29 and 11q22.3-25, may represent general alterations in carcinomas derived from squamous epithelium.

We suspect that the relatively well-preserved GSIS from isolated islets may in both cases therefore represent alterations in β-cell-β-cell (or β-cell-α-cell contact) or between β-cells and the capillary network.

The other weakness of this approach is that DNA methylation can vary by blood cell type, and thus the methylation changes associated with the variables investigated in this study may represent an alteration in blood cell composition, rather than a change in methylation.

We observed that increasing AluYb8 methylation was associated with greater extents of methylation at CpG loci located in a PcG target, and thus a change in the extent of methylation of AluYb8 may represent an alteration in the methylation of these key loci important in tissue development and differentiation.