Sentence examples for may involve alterations from inspiring English sources

Our preliminary findings indicated a loss of delta-opioid receptor-mediated protection in aged vs. young mouse hearts, which may involve alterations in protective kinase signaling.

This may involve alterations in neurotrophin production by Langerhans or other epidermal cells, which in turn may affect mechanical sensitivity directly or as a result of neuropathic changes.

Inflammation and activation of the innate immune system are often associated with traumatic injury and may involve alterations in toll-like receptor (TLR -mediated responses.

It is likely that the selection of cell clones and their adaptation to various culture conditions may involve alterations not only in cellular machinery directly related to the selected marker or adapted behavior, but also those which may or may not be essential for selection or adaptation.

Aβ-induced miRNA regulation may involve alterations in cellular localization that will not only impact function but also turnover rate of miRNAs [52].

Since MstnPP is secreted, possibly for local inhibition of muscle growth [14], post-secretion aggregation or secretion of aggregated/misfolded MstnPP may contribute to muscle fiber atrophy in sIBM via a cytotoxic mechanism that may involve alterations to endo- and exocytosis [65], alterations to Ca2+ homeostasis and the generation of reactive oxygen species [41].

The underlying mechanisms are unclear but may involve alteration in energy-demanding activities, such as protein synthesis.

Gene expression modulation from the integrin by thyroid hormone and tetrac formulations may involve alteration of the states of phosphorylation and acetylation of certain intranuclear receptors, as well as regulation of coactivator/corepressor complex formation [ 17].

The control of p53 signalling output by oncogenic KRAS may therefore involve alterations in p53 post-translational modifications and/or binding partners.

This may involve subtle alterations in clamp position that could alter catalytic properties of RNAP allosterically (Hirtreiter et al, 2010) consistent with normal mode analysis (Yildirim and Doruker, 2004).

These events may involve chromosomal alterations affecting structure and expression of (candidate) oncogenes and tumour suppressor genes, as well as epigenetic alterations.