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The decrease in citrate synthase activity observed in both muscles may reflect mitochondrial impairment.

Therefore, reduced oxidative metabolism may reflect mitochondrial dysfunction in ischemic myocardium as well as in either hypertrophic or dilated cardiomyopathy.

These observations may reflect mitochondrial heteroplasmy in the form of structural rearrangements.

The altered dATP level in AD, without significant alteration in the other three dNTPs, implies an imbalance in dNTP pools that may reflect mitochondrial dysfunction [ 39].

Fever is reported more frequently with higher propofol infusion rates and this may reflect mitochondrial uncoupling and energy dissipation as heat.

The altered expression of proteins from metabolic pathways may reflect mitochondrial dysfunction as a feature of the transition from compensated myocardial hypertrophy with preserved fatty acid metabolism [ 9] to impaired energy metabolism in heart failure [ 27].

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Similar(53)

These studies were performed at rest, however, and may not reflect mitochondrial function during exercise.

The expression of mitochondrial ADP/ATP translocase 2 and ATP synthase beta chain genes is also increased, and this may reflect abnormal mitochondrial function upon injury.

This may reflect either mitochondrial mitoptosis in damaged and 'primed' tissues, or necrotic loss of similar cells that were 'primed', resulting in elevated mtDNA : nDNA ratio after ischemia.

In contrast, our results demonstrate that uncoupled, maximal respiration may be a more sensitive parameter to reflect mitochondrial dysfunction in sepsis.

Recent support has also been given to the idea that type 2 diabetes is not necessarily associated with impaired mitochondrial function but may reflect differences in mitochondrial volume.

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