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Although molecular targeting may promote cellular uptake, the targeting ligand also affects the overall biodistribution of the carrier.
Consequently, these findings indicate that telomerase may promote cellular survival in epithelial cells by suppressing jnk-dependent caspase-mediated apoptosis.
Thus, sirtuin HDACs may act as cancer suppressors while under other circumstances they may promote cellular malignancy (Voelter-Mahlknecht and Mahlknecht 2010).
On the other hand, increased O-GlcNAcylation of other proteins may promote cellular protection by increasing their binding to Hsp70 [ 48].
While the greater energy availability may promote cellular growth, it may be counteracted by ketones' inhibition of pyrimidine synthesis [ 45], alteration of cerebral nucleotide bio-synthesis and of cerebral amino acid metabolism [ 13, 48].
However, it has been suggested that lipid peroxide breakdown products may promote cellular defence mechanisms, such as induction of signalling pathways, resulting in up-regulation of anti-inflammatory mediators, and inhibition of signalling pathways which control pro-inflammatory mediator expression.
Similar(49)
Modulating the size and density of macropores may promote desirable cellular processes at different stages of tissue development.
It suggested that NADPH oxidase may promote the cellular structure destruction in podocytes.
Thus, it may be that whilst some CD44 isoforms provide a protective role, others may promote adverse cellular features that could favour tumour progression.
Especially in long-lived animals, somatic genome instability can lead to the accumulation of genetic insults that may promote aberrant cellular behavior, ultimately leading to lethal diseases such as cancer.
Therefore, a variety of strategies, including blocking proinflammatory cytokines [ 25], inhibiting MMP activity [ 26, 79], and/or using anabolic growth factors [ 24] to increase matrix synthesis and promote cellular proliferation, may be required to promote meniscal healing following an injury and to increase the success of tissue engineering constructs.
Related(20)
may promote molecular
may promote gastric
may stimulate cellular
may phosphorylate cellular
may protect cellular
may distort cellular
may diminish cellular
may promote diaphragmatic
may affect cellular
may lead cellular
may exhaust cellular
may promote abiotic
may control cellular
may promote mature
may promote human
may induce cellular
may change cellular
may provide cellular
may promote neuroprotective
may coordinate cellular
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