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Crawling large complex graphs is challenging by itself that may need extensive and specialized research efforts.
For example, projects targeting a best-in-class drug candidate may need little exploratory biology and strong chemistry support, whereas those targeting a first-in-class drug may need extensive exploratory biology and a small, but long-term chemistry commitment since relatively little may be known to connect MOA with a human disease state.
This serves to emphasize that verbal labels may need extensive research to ensure the intended message is conveyed.
It thus remains a challenge to identify which TKA candidates will likely do well, or do poorly following TKA and may need extensive rehabilitation [ 2, 9].
Patients with no prior experience with ESRD treatments may need extensive education on how ESRD and its treatments could impact multiple aspects of their lives, while patients with treatment experience may need more focused information about how treatment alternatives might change their treatment experiences.
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You may not need extensive warranty coverage on a vehicle you're leasing for a year or two.
The valuation is attractive and Reed would probably outperform in a downturn, but a sizeable re-rating may need more extensive corporate action.
These findings suggest that men may need more extensive – or different forms – of mindfulness training in order to obtain satisfactory benefits.
Some patients with a large preoperative deformity seen on standing radiographs will not need releases, whereas others with smaller axial deviations may need an extensive release to correct the leg axis.
The mother is in regular contact with the health services during pregnancy and infant/toddler years, and routine screening for maternal risk drinking, for instance with T-ACE, may help target intervention programs and provide early identification of women and children who may need particularly extensive follow-up or support.
The monthly premiums may cost more than having your teeth cleaned, and may not offer that many benefits if you need extensive work done.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com