Sentence examples for may modulate disease from inspiring English sources

Thus, there is compelling evidence suggesting that the Notch pathway is activated in RA and may modulate disease activities.

Evidence further suggests that TMEM106B risk genotypes/increased TMEM106B expression may modulate disease risk by affecting progranulin pathways.

However, this generalisation does not always hold true, and it is possible that environmental factors and/or nuclear genetic influences may modulate disease manifestations.

However, our preliminary data suggest that MBL, and to a lesser extent FCN2, may modulate disease manifestations of SSc, particularly in diffuse cutaneous disease.

Besides differences in size, post-translational modifications of Aβ – including oxidation, phosphorylation, nitration, racemization, isomerization, pyroglutamylation, and glycosylation – generate a plethora of peptides with different physiological and pathological properties that may modulate disease progression.

The genetic susceptibility of Type 1 diabetes is strongly associated with HLA-DQ and DR on chromosome 6, but genetic factors on other chromosomes such as the insulin gene on chromosome 11 and the cytotoxic T-lymphocyte antigen gene on chromosome 2 may modulate disease risk [ 59].

The weak associations identified for a number of hypothesised risk factors imply that multiple pathways may be involved in disease development, and as with other multifactorial diseases, gene interactions with environmental factors may also modulate disease risk [ 48- 56].

Since Tacrolimus, is an immunomodulatory drug used for the treatment of some cases of arthritis, we hypothesized that it may modulate periodontal disease.

In favourable cases, one drug may modulate plural disease-relevant targets, a property known as polypharmacology.

Nonetheless, these results may have implications for the human population, as genotype-diet interactions are known to modulate disease risk in MTHFR 677 C>T individuals (31).

Furthermore, biotic interactions may exert natural selection in a manner that depends upon the abiotic context, for example, saline soils can modulate disease pressure in tomato [ 57].