Sentence examples for may mediate tumor from inspiring English sources

CD8+ T-cells may mediate tumor eradication largely through direct CTL activity, but the role of CD4+ T-cells and other cells of the immune system is less clear.

Eosinophils also infiltrate tumors, and may mediate tumor rejection [18], [19].

Further, cystatin C may mediate tumor cell invasion through MAPK/Erk2 signalling pathways.

Since pCSCs has the potential to differentiate into endothelial-like cells [15], we hypothesized that pCSCs may mediate tumor vasculogenesis.

In contrast, emerging data reveal that in certain cellular contexts the IFN/STAT1 pathway may mediate tumor cell growth.

To validate our computational prediction that NRF2 may mediate tumor cell survival in response to arsenic, we generated lung carcinoma cells that were deficient for the expression of NRF2.

Therefore, GA showed little expression of GRP78 but high expression of CHOP and GADD34 may mediate tumor-suppressive effects.

Our data indicate that ETS2 plays a key role in controlling the expression of miR-196b, and miR-196b may mediate the tumor suppressor effects of ETS2.

It is known that the signal transfer of proteoglycans may mediate the tumor metastasis, whereas HSPG is nearly the most powerful proteoglycans, which carries out this function.

In fact, through stable transfection of estrogen receptor alpha into ER-negative human breast cancer cells, we recently demonstrated that ER may mediate breast tumor resistance to taxanes and vinca alkaloids through inhibition of drug-induced apoptotic cell death [ 27].

Isolation and reinfusion of neoantigen-specific T cells may be required to mediate tumor regression without inducing on-target but off-tumor toxicities (Klebanoff et al., 2016).