Sentence examples for may regulate tumor from inspiring English sources
These results provide a new mechanism for mROS production in GC cells after TLR4 signaling and show direct role for mROS in regulating tumor growth, which indicate that TLR4 may regulate tumor growth via mROS production and the induction of signaling cascades.
Most recently, several lines of evidence suggest that mislocated EGFR may regulate tumor response to therapy and that plasma membrane-bound EGFR elicits survival signals independent of its kinase activity.
These results suggest that miR-21 may regulate tumor progression through modulation of the tumor microenvironment.
These data demonstrated that LUADT1 may regulate tumor cell growth in vivo.
Ephrin-B2 expression has also been observed in tumor vasculature in a variety of tumor types, suggesting that this ligand may regulate tumor neovascularization [ 51- 53].
Binding of the CXCL12 chemokine to its receptor (CXCR4) may regulate tumor dissemination in prostate tumor cells by enhancing expression of αv β3 integrins [ 40].
Through interaction with these chemokine receptors, LASP-1 may also regulate tumor cell migration or possibly survival.
The Gαq/PLCβ/Fhit complex formation points to a novel signaling pathway that may negatively regulate tumor cell growth.
Altogether, given the role of Nrf2 in antioxidant defense mechanisms coupled with the potential modulation of cellular oxidative status by Carmustine treatment, we hypothesized that Nrf2 may functionally regulate tumor cell sensitivity to the cytotoxic effects of Carmustine, a widely used intracerebral chemotherapeutic agent.
Repressors of BMP-6 and E-cadherin, such as δEF1, may regulate breast tumor progression and metastasis at different stages, including the initial de-differentiation of primary tumor cells and the maintenance of migratory and/or undifferentiated phenotypes.
We analyzed the metronomic CPA-responsive mouse (host) gene sets to elucidate potential upstream regulators, including transcription factors and cytokines that may regulate anti-tumor innate immunity induced by metronomic CPA treatment.
