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These results provide anatomical evidence that MOR activation by endogenous or exogenous agonists may indirectly alter GABAergic neurotransmission in the RVL either through presynaptic interactions between cells or through competing influences on postsynaptic targets.
Alternatively, leptin may indirectly alter chondrocyte activity through altered bone remodeling [ 77] or lipid metabolism [ 78].
Thus, these results suggest that administration of AGN may indirectly alter catecholamine synthesis in the brain, producing pharmacological effects [ 42].
First, lead may indirectly alter bone cell function through changes in the circulating levels of those hormones, particularly 1,25-dihydroxyvitamin D3, which modulate bone cell function.
In this regard, n-3 PUFAs are known to modulate proinflammatory cytokine expression and also reduce cytokine signaling events by displacement of cytokine receptors from their downstream signaling partners, suggesting a further means by which fish oil may indirectly alter redox mechanisms (37, 38).
Similar(55)
We therefore infer that by altering blood flow through the sinusoids, adenosine may thus, indirectly alter eNOS expression.
Therefore, OGW drag may directly alter local PW-fluxes or may indirectly change the general circulation of the middle atmosphere and the PW refractive indexes.
When these rearrangements produce "chimeric genes", they may directly or indirectly alter normal physiological functions, such as pollen abortion.
Additionally, dopamine may act upon ER containing cells to indirectly alter Fos expression, via efferent pathways, in cells that do not express ERs.
Of considerable interest is the emerging data demonstrating that many of these "inert" excipients may produce subtle changes that could directly or indirectly alter the activity of membrane-spanning proteins such as transporters.
Although directly induced lesions may be too low to be detectable above background, it remained possible that radiation could indirectly alter the steady-state levels of damage by changing the physiological state of the tissue or by modulating DNA repair.
Related(20)
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