Sentence examples for may indicate disruption from inspiring English sources

Hence, the accumulation of oxidized Prxs may indicate disruption of cellular redox homeostasis [ 75, 76].

Thus, relocalization of the BRK kinase during PCa development and progression may indicate disruption of a signaling pathway important for maintaining the normal phenotype of prostate epithelial cells.

On the other hand, the alterations in folliculogenesis and prepubertal steroidogenesis may indicate disruption along the hypothalamo pituitary ovarian axis after exposure to either PBDE-99 or A1254.

Although further studies are required, downregulation of Nedd4 in this study may indicate disruption in the removal of misfolded or unwanted proteins causing their accumulation.

Glutathione S-transferase P is involved in the regeneration of reduced thiols [ 41] and therefore the relatively lower levels may indicate disruption to oxidative state in the hypertrophic myocardium.

Alternately, the silcretes may indicate disruptions in the biota.

In the most neophobic strain (BALB/c mice), Groves et al. also found alterations in glutamate and glutamine levels in brain tissue, which may indicate a disruption in glutaminergic neurotransmission.

The apparent discrepancy between the results may indicate that disruption of the intrinsic intestinal microbiota due to antibiotic exposure is not a key feature for C. difficile colonization as it is for progression to disease.

However, the ligase-deficient PIAS1 mutant (W372A/C351S) was not modified by ROS in vivo or phosphorylated by JNK in vitro (Supplemental Fig. S2 E), which may indicate that disruption of the RING-finger motif induces a configurational change that masks putative phosphorylation sites.

Increased T2 values indicate disruption of the collagen matrix and higher water permeability, which may be the earliest physiological changes in cartilage degeneration (Liess et al. 2002, Taylor et al. 2009).

The observed malformations, including hypospadias, indicate disruption of androgen action.