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Deformity and enlargement of fingers may impair normal function.
As these DRM microdomains are involved in many cellular events, an imbalance or disruption of the cell membrane homeostasis may impair normal cell function.
The lack of functional cells may impair normal collagen synthesis and the process of healing [ 11, 16].
Based on theory we hypothesized that in particular the distal rim may impair normal outflow of menstrual blood.
Animal studies have shown that dioxin-like OCs may impair normal bone metabolism and result in increased bone fragility [ 32- 34].
AKI by predisposing to metabolic acidosis may play a detrimental role affecting cerebral neuronal metabolism and may impair normal cerebral function.
Similar(52)
With this methodology, several studies showed inverse relations between cardiac lipid content and systolic and diastolic function [ 9- 11], suggesting that excessive lipid accumulation in the heart may indeed impair normal cardiac function and result in cardiomyopathy and contribute to the increased risk of heart failure in type 2 diabetic patients [ 13].
Chemokines may contribute to SLE by recruiting immune and inflammatory cells to target tissues and by altering the normal trafficking and localization of certain populations of immune cells in the body; hence, they may impair the normal function of such cells.
Since leptin has neurotrophic actions on the development of projections from the ARC [19], such down-regulation may impair the normal development of those projections.
Thus, C-terminal KCNE1 mutations may impair the normal formation of KCNQ1/KCNE1 channels that are successfully trafficked to the plasma membrane.
Children's lungs and immune systems are developing, and exposure to high ozone levels may impair the normal process of development (Plopper and Fanucchi 2000; Trasande and Thurston 2005).
Related(20)
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may impair hepatic
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may impact normal
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