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Disease-associated SNPs may disrupt or engender TF/uDBP binding sites [30].
Repetitive transcranial magnetic stimulation (rTMS) of human cortex may disrupt or facilitate cortical activity.
Solar, geomagnetic, gravitational and seismic activities cause disturbances in the ionospheric region of upper atmosphere that may disrupt or lower the quality of space based communication, navigation and positioning system signals.
Possibly, the researchers noted, memantine may disrupt or hinder the metabolism or absorption of vitamin E. "For people who are in the early stage of Alzheimer's disease, I think any delay in the rate of progression is meaningful and important," said Maurice W. Dysken, the study's lead author.
The S151A-human-SGCD may act as a dominant negative isoform.[6] Accordingly, the expression of the S151A-SGCD may disrupt or, at least, alter the proper functioning of dystrophin glycoprotein complex thereby inhibiting extracellular signals that are necessary to maintain normal myocyte function.
Further, the innovation may disrupt or displace procedures in areas that have been targets of quality improvement.
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The progression from normal cell, subject to stringent growth controls, to an unregulated tumor cell is a stepwise process of accumulating mutations and rearrangements in the genome [ 1], which may disrupt, inhibit or deregulate genes, or create novel fusion genes.
The mechanism of flavin insertion into complex I during assembly is not known, and the mutations may disrupt either (or both) the enzyme affinity for flavin or insertion of flavin into the site.
Since the interim Iraqi government is worried that "bickering" groups may disrupt, subvert or not participate in elections in January, the government should consider adding a two-item referendum to the ballot.
The service was on standby to declare a major incident - defined as something which may disrupt services or require special arrangements to be implemented by health staff - on Saturday 27 December, but was back to normal within days, it said.
The service said it went on standby to declare a major incident - defined as something which may disrupt services or require special arrangements to be implemented by health staff - on Saturday.
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