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RICHARD PELTO Kenmore, Wash., June 27, 2011 To the Editor: Re "Behind Veneer, Doubt on Future of Natural Gas" ("Drilling Down" series, front page, June 27): I hope that the United States Energy Information Administration's "lively debate" about shale gas development not only continues but also expands to include a closer examination of how hydraulic fracturing may affect water resources.

Proposed groundwater withdrawals may affect water content of soils along this gradient.

High levels of hardness may affect water supply system, excessive soap consumption, calcification of arteries and cause urinary concentrations, diseases of kidney of bladder and stomach disorders.

Since natural flow of water in winters is lean; and tourist activity during December Christmass and New Year) is more, it may affect water quality adversely particularly during this period.

Results are compared with current water resources development and ecosystem services in each watershed to gain insight into how regional climate warming may affect water supply, hydropower generation, and montane ecosystems.

Adoption of these regulations (or non-adoption) may affect water quality and forest cover around UPDE and DEWA (Kargbo et al. 2010).

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iii) H3K64 acetylation may affect water-mediated hydrogen bonds that directly influence association of histone dimers.

Alternatively, following the loss of H2A H2B dimers H3K64ac may favour dissociation of DNA from histones H3 and H4, or H3K64ac may affect water-mediated hydrogen bonds that directly influence the association of H2A H2B dimers.

For example, interpersonal variation in amount of water consumed may affect urine output.

The changes associated with climate may severely affect water availability, agricultural production, and hydropower generation in downstream areas (Immerzeel et al. [2010]), and thus have an impact on the livelihoods of a large number of people living in the transition and flood plain zones.

Fire retardant may also affect water quality through leaching, eutrophication, or misapplication.

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