Sentence examples for maximal uptake in from inspiring English sources

The internalization of nanoparticles by cells is believed to be accomplished predominantly by receptor-mediated endocytosis, and particle size is an important variable in determining the kinetics of cellular uptake, with maximal uptake in a size range of 40-50 nm [35, 36].

The slice with maximal uptake in the ROI was chosen for measurement of metabolic activity of the tracer (SUV).

The mean SUV for breast cancer was 8.5 +/- 3.3 (s.d)., while the maximal uptake in the liver was 12.4 +/- 1.6, in the bone marrow 5.8 +/- 0.7, and in the myocardium 3.4 +/- 0.6.

Moreover it is shown that the multi-pinhole SPECT method is able to identify differences in the range of 20% of the maximal uptake in the dose range between 950 kBq/g and 440 kBq/g employed in this study.

The prime aim of any radiopharmaceutical development programme is to produce a metabolically robust radiotracer having a well-defined structure that shows the maximal uptake in target tissues (i.e. tumour in this instance) and minimal uptake in normal, non-target tissues including those involved in metabolism and excretion of the tracer.

Although a focal uptake pattern is most suggestive of CS, several studies have reported that fasting F-FDG uptake is inhomogeneous throughout the left ventricle in healthy subjects [ 61] and in oncologic patients [ 62], with regional maximal uptake in the infero-lateral and basal myocardium, probably because of local differences in substrate use [ 62].

This apparent disparity may reflect the fact that in our study the participants were exposed to elevated levels of DEP and DnBP for only 6 hr, whereas dynamic modeling indicates that > 40 hr would be required to reach steady-state and maximal uptake via the dermal pathway in comparison to the inhalation pathway.

In a recent publication they summarise the kinetics of uptake in 26 patients of various pathologies showing that the time to 80% of maximal uptake was, in most cases, only a few minutes.

The maximal uptake rate in FBA for each amino acid is determined from the literature (i.e., Oberhardt et al., 2008 [ 7 ]).

Our model predicts that the optimal radius of NPs for maximal uptake rate falls in the range of 25 30 nm, and optimally several tens of ligands should be coated onto NPs.

Changes in maximal uptake rate following antagonist injections were expressed as Vmax, and changes in uptake inhibition following cocaine were expressed as apparent Km.