Sentence examples for maximal serum concentrations from inspiring English sources

Time to maximal serum concentrations is approximately 1.5 2 hours, and the elimination half-life is approximately 11 hours.

Therefore, at maximal serum concentrations cellular binding remained at 39% (24 mM curcuminoids), 15% (6 mM) and 12% (4 mM) relative to the respective binding without added serum.

14- 17 Maximal serum concentrations for 3α-monosulfated and -disulfated progesterone metabolites that are elevated in ICP have been shown to reach 4.5 μM and 12 μM, respectively.

Assessment of serum levels of ponazuril showed that the two medication schedules considerably influenced the maximal serum concentrations in the animals.

The maximal serum concentrations of protein S-100 correlated significantly to bypass time (r = 0.7, P = 0.0007), cross-clamping time (r = 0.57, P = 0.001) and minimal rectal temperature during CPB (-0.57, P = 0.001).

Pharmacokinetic data from clinical trials following a twice-daily dose of vorinostat determined that the half-life was in the range of 1 - 3.5 h and maximal serum concentrations did not peak over 2 μM and rapidly diminished [ 27, 42, 43].

The maximal serum concentration of S100 during the investigation correlated with the incidence of SAD (-0.401, P = 0.028).

Maximal serum concentration is reached approximately three hours following oral administration and the peak serum concentration is approximately 20 ng/mL.

The average maximal serum concentration (Cmax) in the NLM group was 1021.04 ± 50.58 pg/mL, which was significantly greater than in the other groups (P <0.001).

Investigated PK parameters included maximal serum concentration (Cmax, calculated by extrapolation of the elimination phase at the end of the infusion) Vd, total clearance (CL), elimination half-live (t1/2) and area under the serum concentration-time curve (AUC).

Values of Cmax (maximal serum concentration) and AUC0-∞ (area under the curve from zero to infinity) following the first dose appeared to increase linearly but were not dose-proportional after the sixth dose.