Sentence examples for maximal plasma concentrations from inspiring English sources

Administration occurred 1 h before testing to reach maximal plasma concentrations.

However, both maximal plasma concentrations and total exposure of bexarotene increased by 80% in the presence of paclitaxel-carboplatin by an, as of yet, unexplained mechanism.

Guided by ionic liquid structure, in vivo profiles ranged from rapid bioavailability and high maximal plasma concentrations to sustained patterns.

These changes resulted in an increased rate of absorption and increased maximal plasma concentrations compared to a commercial, micronised product (Lipantil® Micro) in a pig model.

In case of oracin, this enzyme cooperativity may become important with respect to maximal plasma concentrations, and, by inhibition of 11β-HSD 1, to enhance the chemotherapeutic efficacy of this anti-cancer drug.

In animals and in man, the time to maximal plasma concentrations (Tmax) of antibody are typically observed 1 8 days following sc or im administration (Lobo et al., 2004).

Vigabatrin had an oral absorption fraction (Fabs) of 75 80%, and the maximal plasma concentration (Cmax) was reached within 0.5 1.0 h (tmax).

A significant increase in both maximal plasma concentration of drug and area under the drug concentration time curve (AUC) was shown when the particle size was reduced from micrometer to nanometer.

When dosed orally in mice at 50 mg/kg twice a day (BID), 48 showed an unbound maximal plasma concentration (Cmax) >15-fold over its cell EC50, thereby providing a robust chemical probe for studying KDM5 biological functions in vivo.

LND is rapidly absorbed with the maximal plasma concentration occurring at a median time of 0.6 to 1.5 hours after oral administration in healthy human subjects.

By Week 4, mean peak plasma concentration (Cmax) was 865 µg/mL and time of maximal plasma concentration (Tmax) was 39.4 hours.