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A Polish study established a correlation between increased fish consumption and the highest serum concentrations measured in 45 test candidates for 10 fluorochemicals (including PFOS and PFOA) [93].
In Fig. 5, representative TEM images of cells at t = 10 h show that at the highest serum concentrations (25 and 50 % HuS), fewer NPs (1-2 NPs) were found within each intracellular vesicle as compared with for cells exposed to NPs in 10 % HuS or serum-free (0 % HuS) conditions (see also Additional file 1: Figure S3).
We ascribe the residual activity from this serum only seen in the highest serum concentrations to Ficolin-2, which could also fit with the results of the binding experiments.
Deposition of both C4 and C3 was observed in the wells coated with acBSA, while only very small amounts of deposition were seen in the BSA-coated wells incubated with the highest serum concentrations (Figure 3A B).
For BB-153, older adults had the highest serum concentrations.
Mexican Americans had the highest serum concentrations of OC pesticides.
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In mice, rAAV8 vector delivered the highest serum concentration of hAAT (week 2, rAAV8/CB-AT, 19±± 6 μg/ml).
However, even with SPS the Ficolin-3 deficient serum still showed a minimal complement activating activity in the highest serum concentration.
BDE-47 had the highest serum concentration followed by BDE-153; both were detected in 100% of serum samples.
The highest serum concentration tested in the assay was 1 4, and a titer of 1 2 was assigned to sera with <50% killing at this concentration.
High serum concentrations of glucose and advanced glycation end products in people with diabetes induce vascular endothelial dysfunction (VED 3,4.
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