Sentence examples for maximal effect occurred from inspiring English sources

injection of the CCKB receptor antagonist L365,260 produced a dose-dependent (0.125 2.0 mg/kg) potentiation of the analgesia induced by 100 Hz EA, with a maximal effect occurred at 0.5 mg/kg.

Its maximal effect occurred 30 minutes after injection with a decrease of 21±3%3% in the Knee-Bend score (P <0.05, Figure  3E) and an increase of 22 ± 5 in the %TIPPI in the CatWalk test (P <0.05, Figure  3F).

Three hours' hypoxia stimulates microglial cells iInducible nitric oxide synthase (iNOS) gene expression; iNOS gene expression significantly upregulated with its maximal effect occurred at 6 h' culture (up to 23.9 folds of the control).

The pre-incubation of harpagoside can down-regulate hypoxia-induced iNOS gene expression with its maximal effect occurred at 24 h' culture (down to 0.1 folds of the control) (Fig.  4).

The maximal effect occurred at 1 ng/ml Dex, which, perhaps tellingly, also happens to be the minimum dose at which Dex nearly completely suppresses activated T cells on its own.

In this study, 3 h' hypoxia stimulates microglial cells to up-regulate their IL-1β and IL-6 genes expression, with its maximal effect occurred at 6 h' culture.

Studies in healthy volunteers and Parkinson's disease patients have confirmed that the maximal effect occurs with 100 mg to 200 mg tolcapone.

Serum from mice bearing the MAC16 tumour produced an increased protein degradation in isolated gastrocnemius muscle, as measured by tyrosine release, with a maximal effect occurring with serum from animals with a weight loss of between 11 and 20%.

Moreover, we also confirmed that, in control SIECs, MB-cAMP induced a transient increase in ICER mRNA expression, with a maximal effect occurring 3 hours after treatment and returning to approximate basal values by 6 hours (Fig. 5D).

Maximal effects occurred between weeks 10 and 24 of therapy.

Threshold effects were observed with 1 μM Pred, with a number of adherent platelet reduced to 21.8 ± 4 platelets/0.01 mm, while maximal effects occurred at 10 μM Pred, when adherent platelets fell to 6.8 ± 2.9 (hence > 80% reduction; P < 0.01) (Fig. 3B).