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The authors suggested that a blood conservation system is of maximal benefit in patients with higher APACHE II scores, those receiving renal replacement therapy, initial low admission Hb, and longer ICU stays [27].

The findings presented here suggest that iron-folic acid supplementation programs for non-pregnant women are best combined with regular de-worming to achieve maximal benefit in areas where both constitute a public health problem.

Chemotherapy provided maximal benefit in female patients and p53 normal tumours.

The authors suggested that a blood conservation system is of maximal benefit in patients with higher APACHE II scores, those receiving renal replacement therapy, initial low admission Hb, and longer ICU stays [ 27].

In the absence of robust data, many investigators have used combination platinum therapy involving taxane with the rationale that if the addition of a taxane to carboplatin is associated with a survival benefit in advanced disease, then maximal benefit in the stage I curative setting is likely to be best achieved with the combination.

Similar(55)

While the ALTTO trial is still underway (http://clinicaltrials.gov/ct2/show/NCT00490139), the Neo-ALTTO trial showed benefit in both the trastuzumab and lapatinib arms, with maximal benefit seen in the combination arm.

In this context, looking at the subgroups, the >20-ms group remained within the normal range with the maximal benefit seen in the first 6 months.

To obtain the maximal benefit from studies in genetics and genomics there is a need to link this data with the information available in the associated biomedical literature.

4) Global perceived effect will be used to assess satisfaction with treatment and measured by self-assessment on a six-point scale (0 = no benefit, 1 = minimal benefit, 2 = some benefit, 3 = a lot of benefit, 4 = great benefit, 5 = maximal benefit) as used in other studies [ 4, 48, 49].

This highlights that dose adjustment should be considered in order to achieve the maximal benefit of the therapy in routine clinical practice.

In those studies, the maximal benefit of VEGF blockade was observed in combination with chemotherapy.

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