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Exact(12)
Maternal cholesterol, triglyceride, and nonesterified fatty acid concentrations rise during pregnancy (35, 36).
A negative association was found between offspring AA and maternal cholesterol (r = −0.103, P = 0.031).
Our data on both maternal cholesterol and triglyceride levels for all study groups are consistent with several studies [ 47- 52].
An association between maternal BMI and also maternal cholesterol levels and the oxidizability of LDL has been observed [ 33].
Elevated maternal cholesterol in early pregnancy is not a risk factor for first stage caesarean for failure to progress in overweight/obese women.
Overall, neither birth weight nor customized birth weight centile was correlated with randomization measures of maternal cholesterol, HDL cholesterol, LDL cholesterol, C-peptide, or CRP.
Similar(48)
In addition, maternal HDL cholesterol, LDL cholesterol, and total cholesterol were measured in both the Adelaide and New Zealand cohorts from the MiG trial.
Medical records were used to collect data on maternal LDL cholesterol, HDL cholesterol, NHDL-C, triglycerides, and total cholesterol measured at baseline within 6 months prior to conception (V0), at each trimester (V1 V3), and during the first 14 months after delivery (V4) as well as the biometric parameters of the newborns.
Birth weight and customized birth weight centile were not correlated with maternal total cholesterol, LDL cholesterol, or CRP at 36 weeks.
In a multivariate model with fasting glucose, total and HDL-cholesterol, and triglyceride concentrations at 18 weeks, maternal total cholesterol concentration was directly associated with birth weight, abdominal circumference, and MUAC (Table 4).
The power calculations were, however, based on our primary hypothesis concerning the expected difference in maternal total cholesterol levels at week 36 and neonatal total cholesterol levels in the intervention versus the control groups.
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