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Exact(5)

Even when matched for prognostic factors, users of more cardiac rehabilitation sessions (≥70%) were less likely to die over the subsequent 5 years than lower users [124], and program completers had a reduced risk of death and hospitalisation than non-completers [125].

Patients were well matched for prognostic criteria.

However, when matched for prognostic factors (PS and FIGO stage), thrombosis did not impact upon prognosis.

Pretreatment characteristics of the two groups were well matched for prognostic factors (see Table 1).

Paired ER-positive (n = 65) and ER-negative (n = 65) primary breast tumors (n = 130) matched for prognostic factors were assessed.

Similar(55)

Survival data were compared with a control group treated with 60 Gy in 30 daily fractions in a previous MRC study, matched for known prognostic factors.

Fitzpatrick et al. found a five-year OS rate of 30% in the incisional biopsy group as compared to 48% in the excisional biopsy group but the different biopsy groups were not matched for important prognostic factors.

17,18 Further, when matched for other known prognostic factors, melanomas in the head and neck area, upper back, and axial skeleton have a worse prognosis than extremity-based lesions.

31 Nevertheless, adjustment or matching for known prognostic factors should generally be done where possible (for example, using propensity scoring and corresponding analysis, which is an increasingly popular approach 32), while recognising the limitations of such analyses.

A limitation of this study is that the missing data for the remaining patients may mean that the two groups were not well matched for albuminuria, a major prognostic factor for renal decline [ 10].

Controls were matched for gender.

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