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All subjects had normal glucose tolerance and whole-body insulin sensitivity and were matched for physical fitness.
Vastus lateralis muscle biopsies were obtained from 20 healthy 19-yr old men with BWmatched for physical fitness and whole-body glucose disposal, prior to (fasting state) and following a 4-hr hyperinsulinemic euglycemic clamp (insulin stimulated state).
These animals are matched for physical activity but have different memory demands during task performance, and are therefore the appropriate control group for this study.
For example, a different exercise protocol was used and patients and volunteers do not appear to have been matched for physical activity behaviour [ 16].
Recently we reported that in young male smokers, matched for physical activity with control subjects, smoking itself causes a significant decline in skeletal muscle fatigue resistance (Morse et al. 2007).
In summary, resting and maximal ATP turnover are not impaired in people with well-controlled type 2 diabetes, when compared with control subjects matched for physical activity as well as age and weight.
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The importance of matching for physical activity must be noted, as lower muscle ATP turnover rates have been reported in studies comparing type 2 diabetic subjects with non-activity-matched controls (31).
In addition, we found activation differences in visual areas (occipital lobe), despite the fact that the stimuli were matched for their physical features.
At baseline, patients were matched for anthropometric, physical activity, metabolic, and hormonal variables (Table 1).
The three groups were well matched for age, physical characteristics and baseline assessments of SAS, GCS, PI, MAP and HR.
RESEARCH DESIGN AND METHODS Volunteers with (n = 10) and without (n = 10) type 2 diabetes were matched for habitual physical activity, age, sex, and weight.
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