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Long-term damage to the cellular and extracellular components of the bone marrow leads to a rapid decline in the bone marrow-hematopoietic stem/progenitor cells (HS/PCs) compartment.

Metastasis to bone marrow leads to a lengthened T1 relaxation time and signal loss, which contrasts with the surrounding high signal marrow fat.

A T cell attack on bone marrow leads to the apoptosis of CD34+ cells, resulting in pancytopenia and symptoms of bone marrow failure [ 1, 2].

In AML, rapid growth of abnormal white blood cells in the bone marrow leads to a blockage in the production of various cells from other cell lineages.

Our observation that MDS patients showed increased neutrophil ROS response after Maitake treatment suggests that G-CSF induction in bone marrow leads to HPC maturation and release of more functionally competent cells [ 18].

Deletion of Ago2 in bone marrow leads to reduced expression of several other miRNAs in addition to miR-451 [ 43], notably some of the miRNAs that are most preferentially exported from various different cell types.

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At the beginning of this year, as Pope John Paul II prepared the Roman Catholic Church's historical apology and its appeal for reconciliation between Christians and Jews, the shared marrow led to a remarkable meeting of two distant worlds, as the Barrys journeyed to Tonco, population 800 ,to meet the Trevisans.

In the heart, the transplantation of adult progenitor cells derived from either adipose tissue or bone marrow led to a decrease in myocardial pro-inflammatory and pro-apoptotic signaling and, thus, to cardiac protection against ischemia [ 85].

Marrow stimulation treatment primarily aims to recruit mesenchymal stem cells (MSCs) from bone marrow, which leads to coverage of the lesion with fibrous cartilage (Giannini et al. 2009; Hangody et al. 2001; Kono et al. 2006).

Inherited diseases now known to be caused by telomerase defects include certain forms of a condition called "congenital aplastic anemia", in which insufficient cell divisions in the stem cells of the bone marrow lead to severe anemia.

However genetic deletion of PECAM-1 on transferred cells or recipient bone marrow lead to an increase in the number of cells accumulating on blood vessels in the bone marrow vasculature.

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