markers that failed

USAGE SUMMARY

The phrase "markers that failed" is correct and usable in written English.
It can be used to refer to specific markers or indicators that did not perform as expected or did not achieve their intended purpose. Example: "In the experiment, we identified several markers that failed to show the expected results, leading us to reevaluate our methodology."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

12 human-written examples

However, there were 61 N-type markers that failed to match the current reference genome sequence.

BMC Genomics

Markers that failed Hardy Weinberg equilibrium in controls or were missing >10% of genotypes were excluded from analyses.

Human Molecular Genetics

Finally, markers that failed to be assigned with confidence to only one LG were not considered in further analysis.

G3: Genes, Genomes, Genetics

Diamandis provided accounts of initially promising tumor markers that failed to make it into clinical practice because of errors made during validation of the markers' clinical performance [ 4].

Clinical Proteomics

All markers that failed to amplify were therefore rechecked by performing a repeat PCR and the majority amplified at the second PCR attempt.

BMC Genomics

Several candidate markers that failed validation in univariate and multivariate analyses such as Chrom19 deletion, Chrom8q amplification, and BAP1 and TP53 mutations had low prevalence ≤10%.

European Urology

Human-verified similar examples from authoritative sources

Similar Expressions

48 human-written examples

The flag_hw module flags markers that fail Hardy Weinberg equilibrium.

Bioinformatics

Eliminating markers that fail HWE tests also may be eliminating SNPs associated with the disease.

G3: Genes, Genomes, Genetics

Previous work has identified that it is worth retesting any markers that fail to amplify at the first PCR attempt [ 21].

BMC Genomics

Markers with minor allele frequency <1%, SNPs with >5% missing genotypes and, any marker that failed an exact test of Hardy Weinberg equilibrium (P < 10−7) were excluded from further analyses.

Human Molecular Genetics

In contrast, only two of the eight candidate genetic markers that had failed univariate validation were enriched in ccB samples (Supplemental Fig. 5), and the median number of these aberrations between ccA and ccB samples was not statistically different (Fig. 4C and 4D).

European Urology

Expert writing Tips

Best practice

When discussing research outcomes, clearly specify the criteria for marker failure to provide context and avoid ambiguity. For example, state "markers that failed to meet the significance threshold of p < 0.05".

Common error

Avoid broad statements like "all markers failed." Instead, specify which markers failed under which conditions to maintain precision and accuracy in your writing.

Linguistic Context

The phrase "markers that failed" functions as a relative clause, modifying the noun "markers". It describes a subset of markers based on their lack of success or expected performance. This aligns with Ludwig's assessment that the phrase is usable in written English.

Expression frequency: Common

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Encyclopedias

0%

Ludwig's WRAP-UP

The phrase "markers that failed" is a grammatically correct and commonly used expression, particularly within scientific and academic writing. Ludwig AI confirms its validity and usability. It functions as a relative clause, specifying indicators that did not meet expected criteria. While alternatives like "unsuccessful markers" exist, "markers that failed" maintains a clear and concise meaning within its primary context of scientific research. This analysis highlights the importance of specifying failure criteria and avoiding overgeneralizations when using this phrase.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

unsuccessful markers

Replaces "failed" with a direct synonym, maintaining a similar level of formality.

markers that didn't succeed

Replaces "failed" with a more general term for lack of success.

markers that proved ineffective

Emphasizes the lack of effectiveness of the markers, adding a layer of detail.

markers that were invalidated

Highlights the invalidation aspect of the markers.

markers that didn't work

Uses a more informal contraction and verb choice, suitable for less formal contexts.

markers that lacked validation

Focuses on the deficiency of validation for those markers.

markers which did not validate

Highlights lack of validation for the markers. Somewhat more formal and technical.

markers demonstrated to be inadequate

Emphasizes the inadequacy that was demonstrated by the markers.

markers showing no positive result

Focuses on the absence of a positive outcome from the markers.

markers that missed the mark

Uses an idiomatic expression to indicate failure to achieve the intended outcome.

FAQs

How can I use "markers that failed" in a sentence?

You can use "markers that failed" to describe indicators that did not perform as expected. For example, "The study identified several "markers that failed" to show a significant correlation with disease progression".

What are some alternatives to "markers that failed"?

Alternatives include "unsuccessful markers", "ineffective markers", or "markers that didn't work", depending on the desired level of formality.

Is it better to say "markers that failed" or "markers that did not succeed"?

Both "markers that failed" and "markers that did not succeed" are grammatically correct. The choice depends on context and desired tone. "Markers that failed" is slightly more concise, while "markers that did not succeed" may sound more formal.

What does it mean when research mentions "markers that failed validation"?

When research mentions "markers that failed validation", it means the markers did not meet the necessary criteria during the validation process. This could be due to inconsistency, lack of reproducibility, or failure to correlate with the intended outcome.