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Genome information has increased dramatically with technological advances [ 7] and consequently the number of candidate markers has increased significantly.
The search for new, powerful, informative-single copy nuclear markers has increased our wealth of information in systematic studies.
The use of SNPs has become standard in QTL mapping, and because of their high frequency in the genome, the number of scored markers has increased considerably from older technologies.
Although the literature of identification of novel miRNA markers has increased rapidly in the last 7 years, we are still in the very initial stage of the clinical-application realm.
Based on our reviewed papers, it is evident that the application of SRAP markers has increased dramatically since their introduction in 2001, especially in the past few years (Fig. 1).
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We aimed to investigate which urinary markers have increased levels in patients with ADPKD; whether these urinary markers are associated with measured glomerular filtration rate (mGFR), ERBF, and total renal volume; and whether these associations are independent of albuminuria (urine albumin excretion [UAE]).
Over the last few years the interest in diagnostic markers for specific diseases has increased continuously.
In the past few years, the list of non-invasive surrogate markers of liver fibrosis has increased progressively.
Thus far, different barley maps have been constructed using EST-derived markers [ 8- 10]; consequently, the potential availability of holistic genetic markers in the Triticeae genome has increased.
The consensus version 4 map consists of ten RIL populations and two F4 breeding populations, which has increased the marker density and improved the marker order.
The number of studies assessing the performance of urine markers to detect bladder cancer has increased rapidly, also in the context of recurrence detection of NMIBC [ 5– 7].
Related(20)
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