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The architecture of the inner mitochondrial membrane (IMM) provides a crucial platform for many mitochondrial functions while mitochondrial network architecture is crucial for coordinating these activities throughout the cell.
Interestingly, these processes likely couple p53 to many mitochondrial functions that include the redox pathways and energy metabolism of the cells [14].
U2OSrho0 cells, which do not contain mitochondrial DNA and thus are defective in many mitochondrial functions, were larger than wild-type cells.
Growing evidence suggests that the delicate equilibrium between mitochondrial fission and fusion is vital for many mitochondrial functions including metabolism, energy production, Ca2+ signalling, ROS production and apoptosis.
Although cellular and genetic developmental processes associated with many mitochondrial functions are highly conserved between these model organisms and humans, cross-species extrapolation should focus on conserved pathways rather than on disease phenotypes to ensure that valid conclusions are drawn.
Similar(55)
Many genes involved in mitochondrial functions were down-regulated and utltrastructural observations revealed many mitochondrial disorders.
Mitosomes have also lost many of the typical mitochondrial functions, such as respiration, the citric acid cycle, and ATP synthesis.
Clearly, it will be important to further assess as many mitochondrial and other cellular functions as possible to dissect the full spectrum of PINK1 pathogenesis.
Many studies suggested that mitochondrial functions become defective as we age.
Larger cells displayed increased expression of cytoskeletal genes but unexpectedly repressed expression of many genes involved in mitochondrial functions.
In addition, many genes associated with mitochondrial functions were differentially expressed, correlated with the likely mode of action of phosphine in insects.
Related(20)
several mitochondrial functions
multiple mitochondrial functions
diverse mitochondrial functions
many mitochondrial genes
many cultural functions
many mitochondrial diseases
many mitochondrial rDNAs
many mitochondrial aaRSs
many mitochondrial mRNAs
many biological functions
many pancreatic functions
many intriguing functions
many putative functions
many mitochondrial proteins
many mitochondrial variants
many known functions
many different functions
many mitochondrial properties
many cellular functions
many mitochondrial nucleoids
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