Sentence examples for many limitations with from inspiring English sources

Traditional breast cancer (BrCa) bone metastasis models contain many limitations with regards to controllability, reproducibility and flexibility of design.

However, a great amount of applied research is still needed, and there are many limitations with these approaches which are described in this review.

There are many limitations with trying to analyse the balance of gastrointestinal and cardiovascular risks for coxibs and NSAIDs.

Additionally, because of the many limitations with retrospective dietary assessment, we focus on results that were reasonably consistent in magnitude and statistical significance between all cases versus controls and self-reporting cases versus controls.

While single center studies have many limitations with respect to multicenter studies or registries, they have the advantage of studying a more homogeneous population and of thus preventing at least one confounding factor.

Many limitations associated with achieving and maintaining large 3-D constructs of cells that are fully differentiated restrict clinical use.

This technique provides clinically relevant information by calculating in-vivo joint contact patterns during dynamic conditions and overcomes many limitations associated with conventional techniques for quantifying joint mechanics.

A new approach to β-delayed neutron spectroscopy has been demonstrated that circumvents the many limitations associated with neutron detection by instead inferring the decay branching ratios and energy spectra of the emitted neutrons by studying the nuclear recoil.

There are many limitations associated with a database analysis such as this one.

As with the body mass index, the body surface area is derived using the patient's height and weight but is associated with many limitations, particularly in those with extreme variation in body composition such as obese patients, leading to under- or overdosing [71].

There were too many limitations and frustrations with working a single design agency.