Sentence examples for many gene mutations from inspiring English sources

Many gene mutations can extend life--at least in fruit flies.

The many gene mutations that make up a brain tumor in one person may not be a proper target in another person's tumor.

However, many gene mutations remain to be discovered.

Use of massive parallel sequencing technologies has changed this outcome, and now many gene mutations have been discovered.

Mutation data are in line with the multi-hit model proposed by Gilliland suggesting that many gene mutations play a role in leukemogenesis [ 16].

As many gene mutations have already been reported to be associated with NTG in demographic studies, increasing reports on transgenic mice with the phenotypes related to human glaucoma have been published (Table 1).

Nonetheless the complex interaction of these markers with many other gene mutations that can modify the final prognostic impact, or the effect of intrinsic mutational characteristics, such as, allelic burden or mutation site on protein function and prognosis, make molecular risk stratification a highly complex process.

PCD is also a genetically heterogeneous disorder with many single gene mutations leading to similar clinical phenotypes.

Finally, many homeobox gene mutations are (or will be) embryonic or perinatal lethal, making analysis of the development of adult organs particularly challenging.

This may have been due to the application of insensitive genetic screening techniques given that direct sequencing revealed many CCM1 gene mutations that had been missed by denaturing high-performance liquid chromatography or SSCP in the past.

While many PLP gene mutations result in the impairment of myelin sheath formation, these mutations are also associated with a substantial decrease in the survival of OLs (Knapp et al., 1986; Boison and Stoffel, 1989; Gow et al., 1998), which has been associated with an accumulation of PLP product in the ER (endoplasmic reticulum) of OLs, leading to apoptosis (Gow et al., 1998).