Sentence examples for multiple gene mutations from inspiring English sources

The application of DNA chip technology includes the comprehensive analysis of multiple gene mutations and expressed sequences with regard to newer drug designs, host pathogen interactions and the design of new vaccines.

Where once it was possible to test tumor samples for only one mutation or genomic rearrangement at a time, NGS technology now enables testing for multiple gene mutations in multiple samples simultaneously.

This heterogeneity is not well understood and it has been suggested that HPE involves a combination of multiple gene mutations.

Increasing transposon number and/or transposase efficiency will also lead to GFP-positive offspring with multiple gene mutations.

A hallmark of cancer cells is the possession of multiple gene mutations and aberrations in cell signaling pathways.

More importantly, using this RNA-guided endonuclease technology, multiple gene mutations and their germline transmission have been achieved [ 28- 30].

The CRISPR/Cas9 system is a highly efficient and convenient genome editing tool, which has been widely used for single or multiple gene mutation in a variety of organisms.

To ascertain if the multiple gene mutation was not false positive, we conducted a whole genome sequencing of the wild type JHN and extensive GBS of selected mutated genes using random lines core collection of the JHN mutant population to see if there have already existed in the JHN.

We speculate that multiple gene mutation or some susceptible genes may be involved in the simultaneous occurrence of both malignancies.

Moreover, the multiple-gene mutations could be inherited by the next generation.

Using this kit, we found that CRISPR/Cas9 could be used to knock out multiple plant genes simultaneously, and the efficiencies of multiple-gene mutations, in accordance with the "Bucket effect" theory in economics, depended on the lowest mutation efficiencies of the targeted genes.