This array consists of 246 breast cancer cases and normal controls, among which 182 malignant tissues were histologically interpretable.
Malignant tissues were also categorized as low expression (score 0+ to 1+) and high expression (score 2+ to 3+) for C2-O-sLex.
Frozen human lung tumor specimens and non malignant tissues were obtained from Cooperative Human Tissue Network, Vanderbilt University Medical Center (Nashville, TN).
The positivity of PP2A-C expression in BPH/benign and malignant tissues were 90.3% (28 out of 31) and 90.6% (58 out of 64), respectively, and the difference was not statistically significant (P-value=0.6).
The staining patterns of malignant tissues were graded and no correlation was found between the grades and survival or indices of prognosis, (the oestrogen receptor status, Bloom's grade and the presence or absence of metastases to the axillary nodes).
The distribution and degree of expression of c-yes-1 gene product in a variety of cell lines, human foetal tissues, and adult normal and malignant tissues were examined using immunohistochemical techniques.
