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Thus, consistent with intuition, the model predicts that the vast majority of sequencing errors will be contributed by bases at the ends of reads in single-coverage regions of an assembly, but somewhat surprisingly, it shows that this property holds even for quite large values of λ.
The majority of sequencing errors was identified within homo-nucleotide stretches (112 differences, 66% of all).
The majority of sequencing errors were substitutions on the Illumina MiSeq and insertions and deletions, mostly in homopolymer regions, on the Ion Torrent PGM.
The focus of most large-scale cancer sequencing projects to date has been on finding mutations in coding regions, with the majority of sequencing projects focusing on transcript sequence.
Due to the extent of the intra-species genomic sequence variation across geographic localities (Russell et al., in preparation), these Illumina data could not be used to supplement the genome assembly but were sufficient to correct the majority of sequencing indel errors in the PacBio reads.
Based on the mathematical analysis the majority of sequencing libraries were sequenced to exhaustion (Table 4).
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Authors' response: In the vast majority of sequenced animal genomes, autonomous Transibs are not present at all.
However, in lung tumors the majority of sequence variation occurred in the coding region.
The marked genetic heterogeneity, poor functional characterization of the vast majority of sequence variations, and an uncertain genotype-phenotype relationship complicate the definition of mutational search strategies.
The majority of sequencing-unique ERs occur in regions where the microarray does not have sufficient probes to confidently identify enrichment (generally, at least three probes are required).
The majority of sequences (67.2% CD and 43.3% non-IBD) were found in the OTU 1.
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