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Exact(5)
While activation and regulation of ERK1/2 have been extensively studied, little is known about the N-terminal region that resides outside of the kinase domain and encompasses the major sequence divergence between ERK1 and 2 (figure 3).
However, the 2010 and 2012 Harris County isolates exhibit major sequence divergence (>0.42%) relative to group 1 6 isolates despite shared geographic distribution and environmental conditions.
Only one of these Torvum induced transcripts has a validated counterpart in eggplant (tor5_c4459, slightly downregulated as a consequence of infection) pointing to major sequence divergence and/or lack of counterparts in eggplants for this set of induced Torvum candidate resistance genes.
Figures 6 and 7 shows high sequence conservation of both inner and outer DysF domains, and confirms that its existence as a nested repeat has not caused major sequence divergence in either its inner or outer version, compared to the unembedded DysF in Pex30p.
We observed a complex history shaped by three successive events well separated in time: (i) an ancestral duplication event specific to teleost fishes corresponding to the WGD; (ii) a parallel loss of one duplicated copy (AR-B) in basal Clupeocephala and (iii) a major sequence divergence indicative of a change in functional constraints in the AR-B duplicate of Percomorphs.
Similar(55)
Overall, the similarity analyses indicated that the sequences of the genes belonging to these varieties and rootstocks were essentially identical, suggesting that the differential behaviour of these species cannot be attributed to major sequence divergences.
For duplicated genes, structural divergence and nucleotide substitution are two major types of sequence divergence [ 36].
INDELs play a major role in causing sequence divergence between closely related DNA sequences in animal, plants, insects and bacteria [ 12].
This is in the average range of r/m ratios for bacteria (Vos and Didelot 2009) and indicates that nucleotide mutations play a major role in generating sequence divergence for the clade as a whole.
This is paradoxical, since SDs are one of the primary forces driving the evolution of structure and function in our genomes and have been linked not only with novel genes acquiring new functions, but also with overall higher DNA sequence divergence and major chromosomal rearrangements.
Interestingly, loci AG3E35B and AG3E37B could not be amplified in A. merus and A. melas, indicating significant sequence divergence from the major malaria vectors in these two minor vector species.
Related(20)
considerable sequence divergence
great sequence divergence
severe sequence divergence
substantial sequence divergence
primary sequence divergence
important sequence divergence
large sequence divergence
greatest sequence divergence
large scale sequence divergence
major matriline divergence
major sequence component
major sequence cut
major voting divergence
major sequence difference
major sequence alteration
major haplotype divergence
major sequence database
major sequence viral
major basal divergence
major expression divergence
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