Sentence examples for major cell cycle from inspiring English sources

In the related green alga, Chlamydomonas reinhardtii, two types of major cell cycle regulating kinases, CDKA and CDKB, are encoded.

Polo-like kinase 1 (Plk1) has emerged in the past few years as a major cell cycle regulator, particularly for cell division.

In particular, the major cell cycle regulator Cyclin-dependent kinase 1 (Cdk1), previously also called p34cdc2, phosphorylates various proteins resulting in the reorganization of the intracellular architecture [1].

Altogether, these results showed that NFAT5 deficiency could impair the expression of major cell cycle regulators in primary cells exposed to pathologic hypertonic stress conditions.

In the present study, we show that the major cell cycle defect in murine embryonic stem (mES) cells occurs in G2/M.

Alteration of cell cycle control by decreased Orc6 expression was due to the induction of p21, a major cell cycle control gene.

To link the effects of tau pathology caused by a FTDP-17 mutation on cell cycle events, major cell cycle-related proteins were investigated.

CDKs play important roles in the major cell-cycle transitions and phases of all eukaryotic organisms either directly or indirectly.

Xenopus egg extract supports all the major cell-cycle transitions in vitro.

Collectively, our findings provide clear evidence that genistein has a specific effect on major cell-cycle regulatory genes and their associated pathways, which include apoptosis (down-regulation of p53) and motility (by cross-signaling to p38; MAPK).

In the present study, metformin blocked cell cycle progression at the G0/G1 phase, which was correlated with a remarkable decrease in the expression of cyclin D1 and phosphorylation of pRb, two major cell-cycle regulators.